Download MdrDB: Mutation-induced drug resistance DataBase

100537

samples
240

proteins
440

drugs
2503

mutations

Content	Core Set	Full Set
MdrDB database Meta data and processed biochemical features from structure files.
- MdrDB feature data (.tsv)	1.15 MB	23.60 MB
MdrDB structure files Processed wild type and mutant protein structures are grouped by mutation types. For each type, the corresponding samples and an overall feature data (.tsv) are included in the .tar.gz file. Each sample contains 5 structure files (i.e., wild type protein, mutant protein, drug, wild type protein-drug complex, and mutant protein-drug complex).
- Deletion PDB files (.tar.gz)	4.18 MB	457.07 MB
- Indel PDB files (.tar.gz)	637.69 KB	38.22 MB
- Insertion PDB files (.tar.gz)	1.25 MB	50.31 MB
- Multiple complex PDB files (.tar.gz)	1.51 MB	113.72 MB
- Multiple substitution PDB files (.tar.gz)	247.71 MB	3.17 GB
- Single substitution PDB files (.tar.gz)	1.15 GB	19.06 GB
MdrDB annotation files Annotation files for proteins and drugs in MdrDB. And intermediate files for DGSC and DepMap.
- Proteins annotation file (.tsv)		6.92 KB
- Drugs annotation file (.tsv)		13.47 KB
- GDSC drug cell line sensitivity file (.tsv)		352.09 KB
- DepMap drug cell line sensitivity file (.tsv)		3.74 KB

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